… the receptors of androgens, progesterone, estrogen, and thyroid hormones, as well as their
… as well as cause female biased sex ratio in amphibians. Simultaneously, the excess of T can …

… in fetus, suggesting that enzyme is not related to male fetal … female mice with transgenic
disruption of 5α-reductase type 1 (… trends pointing toward an increased likelihood of affected 46,…

… a crucial role in embryonic development, cellular differentiation … of steroid hormones is
demonstrated by states of excess and … 5α-reductase (5αR) type 1 and 2 convert GCs and AGs to …

… Human Hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) enzyme shows a high
capacity to produce the highly active estrogen, estradiol, from a precursor hormone, estrone. …

… Mice lacking Rxfp1 or Rln have parturition defects that in part … function and increased
responsiveness to estrogen. In … encoding 5alpha-reductase type 1 (5α-R1) are induced in …

… Moreover, aromatase (CYP19A1) mutations inhibiting the aromatase activity and the
conversion of androgens to estrogens, cause fetal and maternal androgen excess during …

… administration of estradiol (E2) increased concentrations of … Mice lacking intracellular GRs
die of respiratory failure shortly … of active 17β-hydroxyandrogens (17βHSD types 1, 3, 5 or 7) or …

… be converted by steroid-5alpha-reductase (SRD5A) enzymes to … of estrogens, which is
HSD17B12’s primary function. … production and fertility in mice lacking HSD17B3 highlights the …

… of estrogen dominance results from a decline in progesterone action in humans and mice. …
-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif 15, procollagen …

… -estradiol (E2), a most potent estrogen, is produced primarily … that the increased MEPs in
female mice reflects increased … These findings imply that bile acids enable fetal-liver HSCs …